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Product details
Main product information：
Product Name: Exemestane(Aromasin)
CAS: 107868-30-4
MF: C20H24O2
MW: 296.4
Mp: 155.13°C
Assay :99%
Storage temp: Store at -20°C
Appearance:White Or Almost White Crystalline Powder
Packaging: Bubble/ aluminum foil bag/ box
Shipping Method:EMS,DHL,UPS,TNT or FEDEX
Delivery Time: 1working day after receive the payment
Arrive Time:4-7 days
Payment Method: Western Union, MoneyGram, Bank Transfer and paypal.
Grade : Pharmaceutical Grade
MOQ(Min order quantity):10grams.
Manufacture:RongXin
Usage: Pharmaceutical material, Steroid hormone, Anabolin. As a male hormone and anabolic hormones.
Product description
Aromasin is also known as Exemestane, as it is most commonly called, is a very potent AI which works by blocking the aromatase enzyme in the body. This drug was originally developed to help fight breast cancer in women by reducing estrogen which some believe to aid in cancer cell growth. While not quite as strong as Letrozole, Exemestanes is considerably stronger than Anastrozole.
Aromasin is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Exemestanes is also used to help prevent the cancer from returning. Some breast cancers are made to grow faster by a natural hormone called estrogen. Exemestanes decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.It acts by blocking the enzyme aromatase, subsequently blocking the production of estrogen.It is usually not used in women of childbearing age.
Fuction of Exemestane
A) Exemestane for breast cancer prevention:
Chemoprevention of breast cancer is an effective strategy to reduce the incidence of this disease in women at risk. The first agents to show a significant chemopreventive effect were the SERMs tamoxifen and raloxifen. An updated comprehensive analysis of all SERM prevention trials showed that they are able to reduce the incidence of breast cancer in high- and average-risk women, an effect that is sustained by a reduction in ER-positive invasive breast cancer.
B) Exemestane is a third-generation irreversible steroidal inactivator of the aromatase enzyme and is effective in all the treatment settings for breast cancer, including chemoprevention.
In the metastatic setting, exemestane has been extensively investigated as the first-line, second-line, and further-line treatment and is now registered for the treatment of postmenopausal women with advanced hormone-receptor-positive breast cancer whose disease has progressed following antiestrogen therapy. Of note, the potential lack of cross-resistance with NSAIs yields additional opportunities in the treatment sequence of endocrine agents. Furthermore, based on clinically meaningful results, exemestane with everolimus represents an effective therapeutic option for a disease that has progressed after exposure to NSAIs.
Exemestane is generally well tolerated, with a side effect profile similar to that of other AIs and including menopausal symptoms, arthralgia, bone loss, and altered lipid metabolism.
Our test Specification
TEST ITEMS |
SPECIFICATION |
RESULTS |
Description |
White Crystalline Powder |
White Powder |
Identification |
Positive |
Positive |
Assay(by HPLC) |
98.0~102.0% |
98.64% |
Absorbance(E25px) |
465~495 |
482.5 |
Melting Point |
191~195°C |
193.5~195.0°C |
Loss On Drying |
0.5%max |
0.19% |
Specific Rotation |
+288°~ +298° |
+290.2° |
Residue On Ignition |
0.1%max |
0.03% |
Related Substances |
Total:1.5%max |
<1.3% |
Test |
Single:0.5%max |
<0.4% |
Residue Solvents |
0.2%max |
0.10% |
Heavy Metals |
20PPm max |
<10PPm |
Conclusion |
The specification conform with enterprise standard. |
|
Rongxin Bio-Tech company’s Competitive Advantage to you
1. Quality: all products are produced under GMP, purity more than 99%.
2. More competitive price from factory directly.
3. Customized:accept,we would supply OEM service for the Peptides,hgh,steriods raw powders and other products.
4. Prompt delivery day :shipment will do within 3 working day after receive payment.
5. Safe shipping: bubble+aluminum bag+carton
6. Payment methods: Money gram, western union,T/T advance or bank transfer payment.
How to Proceed Your Orders?
Step 1
At first,Please let me know the products name and quantity you need, and also the destination country.
Step 2
We send you our products price and offer the suitable shipping method for your reference.
Step 3
You confirm the order and pay us money in advance and tell us the shipping details , including contacting person/company, address, mobile number,ZIP code and your special requirements.
Step 4